Annual reports on fermentation processes, vol. 2 by D. Perlman

By D. Perlman

Summary: the once a year experiences of present learn on fermentation strategies are provided to aid the reader to maintain with advancements in components the place he has restricted or peripheral curiosity. The reports are of significant advancements within the box. issues comprise discussions of fermentation substrates and items from cellulosic fabrics; desktop functions to fermentation strategies; kinetic hysteresis in enzyme Read more...

summary: summary: the once a year stories of present examine on fermentation methods are awarded to help the reader to maintain with advancements in parts the place he has restricted or peripheral curiosity. The reports are of significant advancements within the box. subject matters contain discussions of fermentation substrates and items from cellulosic fabrics; computing device functions to fermentation strategies; kinetic hysteresis in enzyme and fermentation structures; immobilized cells; enzymes of commercial curiosity; amino acids; yeasts; antibiotics; and cytotoxic and antitumor compounds from fermentations

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FLICKINGER AND GEORGE 7. TSAO 42 65. 66. 67. 68. 69. 70. 71. Laskin, A. , in "Annual Reports on Fermentation Processes" (D. Perlman and G. T. ), Vol. 1, p. 151. Academic Press, New York (1977). Laskin, A. , in "Single Cell Protein from Renewable and Non-renewable Resources" (E. L. Gaden and A. E. ), Biotech. Bioeng. Symp. No. 7, p. 91. John Wiley & Sons, New York (1977). Bazua, C. D. and Wilke, C. , in "Single Cell Protein from Renewable and Non-renewable Resources" (E. L. Gaden and A. E. ), Biotech.

The off gas C0 2 , or respiration coefficient (RQ), or some other calculated off gas variable, is also controlled by the substrate feed rate, as is the usual case (10,16). However, the system as designed can manipulate one of the other set point controlled variables to control these measured variables. For example, cell concentration might be altered by manipulating the temperature, or pH, or agitation speed, or airflow rate, or any combination of these if it were desired to do this. In a similar way, the RQ might be altered by changing the temperature or pH, etc.

The economics of any of the large-volume fermentation products mentioned could be dramtcially improved with as little as a 2-5-fold increase in concentration in the final fermentation broth. Product yields and productivity may be improved by cell recycle and multistage continuous systems. Concentration, however, may require less emphasis on sophisticated computer coupled process control, and more emphasis on fundamental biochemical and genetic studies concerning the biochemistry of product inhibition and enzyme regulation.

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